Regional heterogeneity of α-adrenoreceptor subtypes in arteriolar networks of mouse skeletal muscle
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چکیده
منابع مشابه
Connexin expression and conducted vasodilation along arteriolar endothelium in mouse skeletal muscle.
Functional hyperemia requires the coordination of smooth muscle cell relaxation along and between branches of the arteriolar network. Vasodilation is conducted from cell to cell along the arteriolar wall through gap junction channels composed of connexin protein subunits. Within skeletal muscle, it is unclear whether arteriolar endothelium, smooth muscle, or both cell layers provide the cellula...
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Stimulation characteristics that determine arteriolar dilation in skeletal muscle.
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In the rat intestinal and cerebral microvasculatures, acute d-glucose hyperglycemia suppresses endothelium-dependent dilation to ACh without affecting endothelium-independent dilation to nitroprusside. This study determined whether acute hyperglycemia suppressed arteriolar wall nitric oxide concentration ([NO]) at rest or during ACh stimulation and inhibited nitroprusside-, ACh- or contraction-...
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To determine whether nitric oxide (NO), adenosine (Ado) receptors, or ATP-sensitive potassium (K(ATP)) channels play a role in arteriolar dilations induced by muscle contraction, we used a cremaster preparation in anesthetized hamsters in which we stimulated four to five muscle fibers lying perpendicular to a transverse arteriole (maximal diameter approximately 35-65 microm). The diameter of th...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2010
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2010.194993